Поддерживает через pdo драйвер такие бд: MySQL, MariaDB, SQLite, PostgreSQL and CUBRID

    require 'rb.php';
    R::setup();
    R::setAutoResolve( TRUE );        //Recommended as of version 4.2
    $post = R::dispense( 'post' );
    $post->text = 'Hello World';

    $id = R::store( $post );          //Create or Update
    $post = R::load( 'post', $id );   //Retrieve
    R::trash( $post );                //Delete

http://redbeanphp.com/